Who it's for: People whose LDL isn't at goal on a statin, post-ACS patients, or those needing additional LDL lowering.
Find what's right for you — take the quizIMPROVE-IT demonstrated that adding ezetimibe to statin therapy after acute coronary syndrome further lowered LDL and improved cardiovascular outcomes.
Works by blocking cholesterol absorption in the gut — a different mechanism than statins.
The total events analysis showed ezetimibe + statin prevented more MIs and strokes.
— Generally well-tolerated.
— Liver function: Discuss with clinician when combining with a statin.
— Not a first-line standalone therapy — positioned as an add-on.
No. Ezetimibe blocks cholesterol absorption in the gut, while statins reduce production in the liver.
Yes, but it's most commonly used as an add-on. Your clinician will determine the right approach.